Plixorafenib (PLX8394)
Product Specifications
CAS Number
1393466-87-9
Target
Raf
Applications
MAPK
Smiles
C1CC1C2=NC=C (C=N2) C3=CC4=C (NC=C4C (=O) C5=C (C=CC (=C5F) NS (=O) (=O) N6CCC (C6) F) F) N=C3
Molecular Formula
C25H21F3N6O3S
Additionnal Information
Plixorafenib (PLX8394) is a next-generation, orally available, small-molecule BRAF inhibitor with IC50 values of 3.8 nM, 14 nM and 23 nM for BRAF (V600E), WT BRAF and CRAF respectively. It has potential antineoplastic activity.
Storage Conditions
3 years -20°C powder
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
K0021503 1.0 µg DNA
ABCF3 sgRNA CRISPR Lentivector (Human) (Target 2)
Sign In for Pricing
View Details PC28052-01 500 mg
(3E) -1,1,1-Trifluoro-4-[ (2-fluorophenyl) amino]but-3-en-2-one
Sign In for Pricing
View Details