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CGP 57380

Product Specifications

CAS Number

522629-08-9

Target

MNK

Applications

MAPK

Smiles

C1=CC (=CC=C1NC2=C3C (=NC=NC3=NN2) N) F

Molecular Formula

C11H9FN6

Additionnal Information

CGP 57380 is a potent MNK1 inhibitor with IC50 of 2.2 μM, exhibiting no inhibitory activity on p38, JNK1, ERK1 and -2, PKC, or c-Src-like kinases. CGP 57380 upregulates β-catenin and potentiates radiation-induced apoptosis.

Storage Conditions

2 years -80 in solvent

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