ISRIB (trans-isomer)
Product Specifications
CAS Number
1597403-47-8
Target
PERK
Applications
Apoptosis
Smiles
C1CC (CCC1NC (=O) COC2=CC=C (C=C2) Cl) NC (=O) COC3=CC=C (C=C3) Cl
Molecular Formula
C22H24Cl2N2O4
Additionnal Information
ISRIB (trans-isomer), the trans-isomer of ISRIB, is a potent and selective PERK inhibitor with IC50 of 5 nM and does not have global effects on translation, transcription, or mRNA stability in non-stressed cells.
Storage Conditions
2 years -80 in solvent
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