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XL388

Product Specifications

CAS Number

1251156-08-7

Target

MTOR

Applications

PI3K/Akt/mTOR

Smiles

CC1=C (C=CC (=C1F) S (=O) (=O) C) C (=O) N2CCOC3=C (C2) C=C (C=C3) C4=CN=C (C=C4) N

Molecular Formula

C23H22FN3O4S

Additionnal Information

XL388 is a highly potent, selective, ATP-competitive inhibitor of mTOR with IC50 of 9.9 nM, 1000-fold selectivity over the closely related PI3K kinases.

Storage Conditions

2 years -80 in solvent

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