Doravirine
Product Specifications
CAS Number
1338225-97-0
Synonyms
MK-1439
Target
Reverse Transcriptase
Applications
Microbiology
Smiles
CN1C (=NNC1=O) CN2C=CC (=C (C2=O) OC3=CC (=CC (=C3) C#N) Cl) C (F) (F) F
Molecular Formula
C17H11C1F3N5O3
Additionnal Information
Doravirine is a novel HIV-1 nonnucleoside reverse transcriptase inhibitor with IC50 values of 12, 9.7, and 9.7 nM against the wild type (WT) and K103N and Y181C reverse transcriptase (RT) mutants, respectively, in a biochemical assay. It is highly specific with minimum off-target activities.
Storage Conditions
3 years -20°C powder
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