Motesanib (AMG-706)
Product Specifications
CAS Number
453562-69-1
Target
VEGFR
Applications
Protein Tyrosine Kinase
Smiles
CC1 (CNC2=C1C=CC (=C2) NC (=O) C3=C (N=CC=C3) NCC4=CC=NC=C4) C
Molecular Formula
C22H23N5O
Additionnal Information
Motesanib (AMG-706) is an orally bioavailable receptor tyrosine kinase inhibitor with IC50 values of 2 nM, 3 nM, 6 nM, 8 nM, 84 nM, 59 nM for VEGFR1, VEGFR2, VEGFR3, Kit, PDGFR and Ret, respectively.
Storage Conditions
3 years -20°C powder
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