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Lesinurad

Product Specifications

CAS Number

878672-00-5

Synonyms

RDEA 594, RDEA-594, RDEA594

Target

OAT

Applications

Transmembrane Transporters

Smiles

C1CC1C2=CC=C (C3=CC=CC=C23) N4C (=NN=C4Br) SCC (=O) O

Molecular Formula

C17H14BrN3O2S

Additionnal Information

Lesinurad (RDEA-594) is a selective uric acid reabsorption inhibitor (SURI) under investigation for treatment of gout in combination with xanthine oxidase inhibitors. Lesinurad is a URAT1 and OAT inhibitor, is determined to be a substrate for the kidney transporters OAT1 and OAT3 with Km values of 0.85 and 2 μM, respectively.

Storage Conditions

2 years -80 in solvent

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