Ertugliflozin L-pyroglutamic acid
Product Specifications
CAS Number
1210344-83-4
Synonyms
MK-8835 L-pyroglutamic acid, PF-04971729 L-pyroglutamic acid
Target
SGLT
Applications
GPCR & G Protein
Smiles
CCOC1=CC=C (CC2=C (Cl) C=CC (=C2) C34OCC (CO) (O3) C (O) C (O) C4O) C=C1.OC (=O) C5CCC (=O) N5
Molecular Formula
C27H32ClNO10
Additionnal Information
Ertugliflozin (MK-8835, PF-04971729) L-pyroglutamic acid is a potent, selective and orally active inhibitor of the sodium-dependent glucose cotransporter 2 (SGLT2) with IC50 of 0.877 nM for h-SGLT2. Ertugliflozin has the potential for the treatment of type 2 diabetes mellitus.
Storage Conditions
3 years -20°C powder
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