Linagliptin (GSK2118436)
Product Specifications
CAS Number
668270-12-0
Synonyms
BI-1356
Target
Ferroptosis
Applications
Apoptosis
Smiles
CC#CCN1C2=C (N=C1N3CCCC (C3) N) N (C (=O) N (C2=O) CC4=NC5=CC=CC=C5C (=N4) C) C
Molecular Formula
C25H28N8O2
Additionnal Information
Linagliptin (GSK2118436) is a highly potent, selective DPP-4 inhibitor with IC50 of 1 nM and exhibits a 10,000-fold higher selectivity for DPP-4 than for other dipeptidyl peptidases such as DPP-2, DPP-8, and DPP-9. Linagliptin activates glomerular autophagy in a model of type 2 diabetes. DPP4 mediates ferroptosis in TP53-deficient CRC cells.
Storage Conditions
2 years -80 in solvent
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS1417003 Inquire
Recombinant Pongo abelii E3 ubiquitin-protein ligase Arkadia (RNF111), partial
Sign In for Pricing
View Details 
MBS488060-01 0.2 mg
Anti-hapten 4-hydroxy-3-nitrophenyl acetyl (NP) [B1-8]
Sign In for Pricing
View Details MBS488060-02 5x 0.2 mg
Anti-hapten 4-hydroxy-3-nitrophenyl acetyl (NP) [B1-8]
Sign In for Pricing
View Details 