Linagliptin (GSK2118436)
Product Specifications
CAS Number
668270-12-0
Synonyms
BI-1356
Target
Ferroptosis
Applications
Apoptosis
Smiles
CC#CCN1C2=C (N=C1N3CCCC (C3) N) N (C (=O) N (C2=O) CC4=NC5=CC=CC=C5C (=N4) C) C
Molecular Formula
C25H28N8O2
Additionnal Information
Linagliptin (GSK2118436) is a highly potent, selective DPP-4 inhibitor with IC50 of 1 nM and exhibits a 10,000-fold higher selectivity for DPP-4 than for other dipeptidyl peptidases such as DPP-2, DPP-8, and DPP-9. Linagliptin activates glomerular autophagy in a model of type 2 diabetes. DPP4 mediates ferroptosis in TP53-deficient CRC cells.
Storage Conditions
2 years -80 in solvent
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
![PE Anti-Human IL-4 Antibody[MP4-25D2]](https://cdn.genprice.uk/products/763/68dd14a2061270361e7d0f1f/imageurl/e-ab-f1203d.webp)