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Dapivirine (TMC120)

Product Specifications

CAS Number

244767-67-7

Target

Reverse Transcriptase

Applications

Microbiology

Smiles

CC1=CC (=C (C (=C1) C) NC2=NC (=NC=C2) NC3=CC=C (C=C3) C#N) C

Molecular Formula

C20H19N5

Additionnal Information

Dapivirine (TMC120) is a non-nucleoside inhibitor for HIV reverse transcriptase with IC50 of 24 nM, inhibits a broad panel of HIV-1 isolates from different classes, inclucing a wide range of NNRTI-resistant isolates. Phase 3.

Storage Conditions

2 years -80 in solvent

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