WHI-P154
Product Specifications
CAS Number
211555-04-3
Target
EGFR
Applications
Protein Tyrosine Kinase
Smiles
COC1=C (C=C2C (=C1) C (=NC=N2) NC3=CC (=C (C=C3) O) Br) OC
Molecular Formula
C16H14BrN3O3
Additionnal Information
WHI-P154 is a potent JAK3 inhibitor with IC50 of 1.8 μM, no activity against JAK1 or JAK2, also inhibits EGFR, Src, Abl, VEGFR and MAPK, prevents Stat3, but not Stat5 phosphorylation.
Storage Conditions
2 years -80 in solvent
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