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Golvatinib (E7050)

Product Specifications

CAS Number

928037-13-2

Target

C-Met

Applications

Protein Tyrosine Kinase

Smiles

CN1CCN (CC1) C2CCN (CC2) C (=O) NC3=NC=CC (=C3) OC4=CC (=C (C=C4) NC (=O) C5 (CC5) C (=O) NC6=CC=C (C=C6) F) F

Molecular Formula

C33H37F2N7O4

Additionnal Information

Golvatinib (E7050) is a dual c-Met and VEGFR-2 inhibitor with IC50 of 14 nM and 16 nM, does not inhibit bFGF-stimulated HUVEC growth (up to 1000 nM) . Phase 1/2.

Storage Conditions

2 years -80 in solvent

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