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Semaxanib (SU5416)

Product Specifications

CAS Number

204005-46-9

Synonyms

Semaxinib

Target

VEGFR

Applications

Protein Tyrosine Kinase

Smiles

CC1=CC (=C (N1) C=C2C3=CC=CC=C3NC2=O) C

Molecular Formula

C15H14N2O

Additionnal Information

Semaxanib (SU5416, semaxinib) is a potent and selective VEGFR (Flk-1/KDR) inhibitor with IC50 of 1.23 μM, 20-fold more selective for VEGFR than PDGFRβ, lack of activity against EGFR, InsR and FGFR. Phase 3.Semaxanib (SU5416) can be used to induce animal models of chronic intermittent hypoxia.

Storage Conditions

2 years -80 in solvent

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