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SB705498

Product Specifications

CAS Number

501951-42-4

Target

TRP Channel

Applications

Neuronal Signaling

Smiles

C1CN (CC1NC (=O) NC2=CC=CC=C2Br) C3=NC=C (C=C3) C (F) (F) F

Molecular Formula

C17H16BrF3N4O

Additionnal Information

SB705498 is a TRPV1 antagonist for hTRPV1, antagonizes capsaicin, acid, and heat activation of TRPV1 with IC50 of 3 nM, 0.1 nM and 6 nM, shows a degree of voltage dependence, exhibits >100-fold selectivity for TRPV1 over TRPM8. Phase 2.

Storage Conditions

2 years -80 in solvent

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