AMG-458
Product Specifications
CAS Number
913376-83-7
Target
C-Met
Applications
Protein Tyrosine Kinase
Smiles
CC1=C (C (=O) N (N1CC (C) (C) O) C2=CC=CC=C2) C (=O) NC3=NC=C (C=C3) OC4=C5C=CC (=CC5=NC=C4) OC
Molecular Formula
C30H29N5O5
Additionnal Information
AMG 458 is a potent c-Met inhibitor with Ki of 1.2 nM, ~350-fold selectivity for c-Met than VEGFR2 in cells.
Storage Conditions
2 years -80 in solvent
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