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WAY-600

Product Specifications

CAS Number

1062159-35-6

Target

MTOR

Applications

PI3K/Akt/mTOR

Smiles

C1CN (CCC1N2C3=C (C=N2) C (=NC (=N3) C4=CC5=C (C=C4) NC=C5) N6CCOCC6) CC7=CN=CC=C7

Molecular Formula

C28H30N8O

Additionnal Information

WAY-600 is a potent, ATP-competitive and selective inhibitor of mTOR with IC50 of 9 nM; blocks mTORC1/P-S6K (T389) and mTORC2/P-AKT (S473) but not P-AKT (T308) ; selective for mTOR than PI3Kα (>100-fold) and PI3Kγ (>500-fold) .

Storage Conditions

2 years -80 in solvent

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