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CHIR-124

Product Specifications

CAS Number

405168-58-3

Target

Chk

Applications

Cell Cycle

Smiles

C1CN2CCC1C (C2) NC3=C (C (=O) NC4=C3C=C (C=C4) Cl) C5=NC6=CC=CC=C6N5

Molecular Formula

C23H22ClN5O

Additionnal Information

CHIR-124 is a novel and potent Chk1 inhibitor with IC50 of 0.3 nM in a cell-free assay. It shows 2,000-fold selectivity against Chk2, 500- to 5,000-fold less activity against CDK2/4 and Cdc2.

Storage Conditions

2 years -80 in solvent

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