What is the catalog number for WYE-687?

The catalog number for WYE-687 is S2668-200mg.

What sizes are available for WYE-687?

WYE-687 is available in the following size(s): 200 mg.

WYE-687 is currently made to order / not held in immediate stock. Contact us for lead time.

Are there any special shipping requirements for WYE-687?

WYE-687 is requires dry ice shipping.

Who manufactures WYE-687?

WYE-687 is manufactured by Bimake.

What is the estimated delivery time for WYE-687?

Estimated delivery time for WYE-687 is approximately 15 business day(s), depending on your location.

WYE-687

Product Specifications

CAS Number

1062161-90-3

Target

MTOR

Applications

PI3K/Akt/mTOR

Smiles

COC (=O) NC1=CC=C (C=C1) C2=NC3=C (C=NN3C4CCN (CC4) CC5=CN=CC=C5) C (=N2) N6CCOCC6

Molecular Formula

C28H32N8O3

Additionnal Information

WYE-687 is an ATP-competitive and selective inhibitor of mTOR with IC50 of 7 nM; blocks mTORC1/pS6K (T389) and mTORC2/P-AKT (S473) but no effect observed on P-AKT (T308) . Selectivity for mTOR is greater than PI3Kα (>100-fold) and PI3Kγ (>500-fold) .