Dolutegravir (GSK1349572)
Product Specifications
CAS Number
1051375-16-6
Synonyms
GSK1349572, S/GSK1349572
Target
Integrase
Applications
Microbiology
Smiles
CC1CCOC2N1C (=O) C3=C (C (=O) C (=CN3C2) C (=O) NCC4=C (C=C (C=C4) F) F) O
Molecular Formula
C20H19F2N3O5
Additionnal Information
Dolutegravir is a two-metal-binding HIV integrase inhibitor with IC50 of 2.7 nM in a cell-free assay, modest activity against raltegravir-resistant signature mutants Y143R, Q148K, N155H, and G140S/Q148H.
Storage Conditions
2 years -80 in solvent
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