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WYE-125132 (WYE-132)

Product Specifications

CAS Number

1144068-46-1

Target

MTOR

Applications

PI3K/Akt/mTOR

Smiles

CNC (=O) NC1=CC=C (C=C1) C2=NC3=C (C=NN3C4CCC5 (CC4) OCCO5) C (=N2) N6CC7CCC (C6) O7

Molecular Formula

C27H33N7O4

Additionnal Information

WYE-125132 (WYE-132) is a highly potent, ATP-competitive mTOR inhibitor with IC50 of 0.19 nM; highly selective for mTOR versus PI3Ks or PI3K-related kinases hSMG1 and ATR.

Storage Conditions

2 years -80 in solvent

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