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PF-04929113 (SNX-5422)

Product Specifications

CAS Number

908115-27-5

Target

HSP (HSP90)

Applications

Cytoskeletal Signaling

Smiles

CC1 (CC2=C (C (=O) C1) C (=NN2C3=CC (=C (C=C3) C (=O) N) NC4CCC (CC4) OC (=O) CN) C (F) (F) F) C

Molecular Formula

C25H30F3N5O4

Additionnal Information

PF-04929113 (SNX-5422) is a potent and selective HSP90 inhibitor with Kd of 41 nM and induces Her-2 degradation with IC50 of 37 nM. Phase 1/2.

Storage Conditions

2 years -80 in solvent

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