SNX-2112

908112-43-6

PF-04928473

HSP (HSP90)

Cytoskeletal Signaling

CC1 (CC2=C (C (=O) C1) C (=NN2C3=CC (=C (C=C3) C (=O) N) NC4CCC (CC4) O) C (F) (F) F) C

C23H27F3N4O3

SNX-2112 selectively binds to the ATP pocket of HSP90α and HSP90β with Ka of 30 nM and 30 nM, uniformly more potent than 17-AAG.

2 years -80 in solvent