GSK256066
Product Specifications
CAS Number
801312-28-7
Target
PDE
Applications
Metabolism
Smiles
CC1=CC (=CC2=C (C (=CN=C12) C (=O) N) NC3=CC (=CC=C3) OC) S (=O) (=O) C4=CC=CC (=C4) C (=O) N (C) C
Molecular Formula
C27H26N4O5S
Additionnal Information
GSK256066 is a selective PDE4B (equal affinity to isoforms A-D) inhibitor with IC50 of 3.2 pM, >380,000-fold selectivity versus PDE1/2/3/5/6 and >2500-fold selectivity against PDE4B versus PDE7.Phase 2.
Storage Conditions
2 years -80 in solvent
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