Tubacin
Product Specifications
CAS Number
537049-40-4
Target
HDAC
Applications
DNA Damage/DNA Repair
Smiles
C1C (OC (OC1C2=CC=C (C=C2) CO) C3=CC=C (C=C3) NC (=O) CCCCCCC (=O) NO) CSC4=NC (=C (O4) C5=CC=CC=C5) C6=CC=CC=C6
Molecular Formula
C41H43N3O7S
Additionnal Information
Tubacin is a highly potent and selective, reversible, cell-permeable HDAC6 inhibitor with an IC50 of 4 nM in a cell-free assay, approximately 350-fold selectivity over HDAC1. Tubacin reduces the replication of the Japanese Encephalitis Virus via the decrease of viral RNA synthesis.
Storage Conditions
2 years -80 in solvent
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