BMS-794833
Product Specifications
CAS Number
1174046-72-0
Target
C-Met
Applications
Protein Tyrosine Kinase
Smiles
C1=CC (=CC=C1C2=CNC=C (C2=O) C (=O) NC3=CC (=C (C=C3) OC4=C (C (=NC=C4) N) Cl) F) F
Molecular Formula
C23H15ClF2N4O3
Additionnal Information
BMS-794833 is a potent ATP competitive inhibitor of Met (c-Met) /VEGFR2 with IC50 of 1.7 nM/15 nM, also inhibits Ron, Axl and Flt3 with IC50 of <3 nM; a prodrug of BMS-817378. Phase 1.
Storage Conditions
2 years -80 in solvent
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