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KW-2449

Product Specifications

CAS Number

1000669-72-6

Target

Aurora Kinase

Applications

Cell Cycle

Smiles

C1CN (CCN1) C (=O) C2=CC=C (C=C2) C=CC3=NNC4=CC=CC=C43

Molecular Formula

C20H20N4O

Additionnal Information

KW-2449 is a multiple-targeted inhibitor, mostly for Flt3 with IC50 of 6.6 nM, modestly potent to FGFR1, Bcr-Abl and Aurora A; little effect on PDGFRβ, IGF-1R, EGFR. Phase 1.

Storage Conditions

2 years -80 in solvent

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