KW-2449
Product Specifications
CAS Number
1000669-72-6
Target
Aurora Kinase
Applications
Cell Cycle
Smiles
C1CN (CCN1) C (=O) C2=CC=C (C=C2) C=CC3=NNC4=CC=CC=C43
Molecular Formula
C20H20N4O
Additionnal Information
KW-2449 is a multiple-targeted inhibitor, mostly for Flt3 with IC50 of 6.6 nM, modestly potent to FGFR1, Bcr-Abl and Aurora A; little effect on PDGFRβ, IGF-1R, EGFR. Phase 1.
Storage Conditions
2 years -80 in solvent
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