Sonidegib
Product Specifications
CAS Number
956697-53-3
Synonyms
NVP-LDE225, Erismodegib
Target
Hedgehog/Smoothened
Applications
Stem Cells & Wnt
Smiles
CC1CN (CC (O1) C) C2=NC=C (C=C2) NC (=O) C3=CC=CC (=C3C) C4=CC=C (C=C4) OC (F) (F) F
Molecular Formula
C26H26F3N3O3
Additionnal Information
Sonidegib is a Smoothened (Smo) antagonist, inhibiting Hedgehog (Hh) signaling with IC50 of 1.3 nM (mouse) and 2.5 nM (human) in cell-free assays, respectively. Phase 3.
Storage Conditions
2 years -80 in solvent
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
042824 200 µL
TIAM2, NT (TIAM2, KIAA2016, STEF, T-lymphoma invasion and metastasis-inducing protein 2, SIF and TIAM1-like exchange factor)
Sign In for Pricing
View Details 
VAng-Ly2076-50gEcoli 50 µg (E. coli)
Recombinant Campylobacter Jejuni cmoB Protein (aa 1-291) (strain 81116 / NCTC 11828)
Sign In for Pricing
View Details MBS1061169 Inquire
Recombinant Meyerozyma guilliermondii Protein TIF31 homolog (TIF31), partial
Sign In for Pricing
View Details