TWS119

Product Specifications

CAS Number

601514-19-6

Target

GSK-3

Applications

PI3K/Akt/mTOR

Smiles

C1=CC (=CC (=C1) N) C2=CC3=C (N2) N=CN=C3OC4=CC=CC (=C4) O

Molecular Formula

C18H14N4O2

Additionnal Information

TWS119 is a GSK-3β inhibitor with IC50 of 30 nM in a cell-free assay; capable of inducing neuronal differentiation and may be useful to stem cell biology. GSK-3β inhibition triggers autophagy.

Storage Conditions

2 years -80 in solvent

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