RO4929097 (RG-4733)
Product Specifications
CAS Number
847925-91-1
Synonyms
RG-4733
Target
Beta Amyloid
Applications
Neuronal Signaling
Smiles
CC (C) (C (=O) NCC (C (F) (F) F) (F) F) C (=O) NC1C2=CC=CC=C2C3=CC=CC=C3NC1=O
Molecular Formula
C22H20F5N3O3
Additionnal Information
RO4929097 (RG-4733) is a γ secretase inhibitor with IC50 of 4 nM in a cell-free assay, inhibiting cellular processing of Aβ40 and Notch with EC50 of 14 nM and 5 nM, respectively. Phase 2.
Storage Conditions
2 years -80 in solvent
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