Hesperadin
Product Specifications
CAS Number
422513-13-1
Target
Aurora Kinase
Applications
Cell Cycle
Smiles
CCS (=O) (=O) NC1=CC2=C (C=C1) NC (=C2C (=NC3=CC=C (C=C3) CN4CCCCC4) C5=CC=CC=C5) O
Molecular Formula
C29H32N4O3S
Additionnal Information
Hesperadin potently inhibits Aurora B with IC50 of 250 nM in a cell-free assay. It markedly reduces the activity of AMPK, Lck, MKK1, MAPKAP-K1, CHK1 and PHK while it does not inhibit MKK1 activity in vivo.
Storage Conditions
2 years -80 in solvent
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