What is the catalog number for LY2811376?

The catalog number for LY2811376 is S1528-50mg.

What sizes are available for LY2811376?

LY2811376 is available in the following size(s): 50 mg.

Is LY2811376 in stock?

LY2811376 is currently made to order / not held in immediate stock. Contact us for lead time.

Are there any special shipping requirements for LY2811376?

LY2811376 is requires dry ice shipping.

Who manufactures LY2811376?

LY2811376 is manufactured by Bimake.

What is the estimated delivery time for LY2811376?

Estimated delivery time for LY2811376 is approximately 15 business day(s), depending on your location.

LY2811376

Product Specifications

CAS Number

1194044-20-6

Target

BACE

Applications

Neuronal Signaling

Smiles

CC1 (CCSC (=N1) N) C2=C (C=C (C (=C2) C3=CN=CN=C3) F) F

Molecular Formula

C15H14F2N4S

Additionnal Information

LY2811376 is the first orally available non-peptidic β-secretase (BACE1) inhibitor with IC50 of 239 nM-249 nM, that act to decrease Aβ secretion with EC50 of 300 nM, demonstrated to have 10-fold selectivity towards BACE1 over BACE2, and more than 50-fold inhibition over other aspartic proteases including cathepsin D, pepsin, or renin. Phase 1.