Voxtalisib (XL765) Analogue
Product Specifications
CAS Number
1349796-36-6
Synonyms
SAR245409
Target
MTOR
Applications
PI3K/Akt/mTOR
Smiles
CC1=C (C=C (C=C1) C (=O) NC2=CC=C (C=C2) S (=O) (=O) NC3=NC4=CC=CC=C4N=C3NC5=CC (=CC (=C5) OC) OC) OC
Molecular Formula
C31H29N5O6S
Additionnal Information
Voxtalisib (SAR245409, XL765) Analogue is a dual inhibitor of mTOR/PI3K, mostly for p110γ with IC50 of 9 nM; also inhibits DNA-PK and mTOR. Phase 1/2.
Storage Conditions
2 years -80 in solvent
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