Ki8751

Product Specifications

CAS Number

228559-41-9

Target

C-Kit

Applications

Protein Tyrosine Kinase

Smiles

COC1=CC2=C (C=CN=C2C=C1OC) OC3=CC (=C (C=C3) NC (=O) NC4=C (C=C (C=C4) F) F) F

Molecular Formula

C24H18F3N3O4

Additionnal Information

Ki8751 is a potent and selective inhibitor of VEGFR2 with IC50 of 0.9 nM, >40-fold selective for VEGFR2 than c-Kit, PDGFRα and FGFR-2, little activity to EGFR, HGFR and InsR.

Storage Conditions

2 years -80 in solvent

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