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MGCD-265 analog

Product Specifications

CAS Number

875337-44-3

Target

C-Met

Applications

Protein Tyrosine Kinase

Smiles

CN1C=C (N=C1) C2=CC3=NC=CC (=C3S2) OC4=C (C=C (C=C4) NC (=S) NC (=O) CC5=CC=CC=C5) F

Molecular Formula

C26H20FN5O2S2

Additionnal Information

MGCD-265 is a potent, multi-target and ATP-competitive inhibitor of c-Met and VEGFR1/2/3 with IC50 of 1 nM, 3 nM/3 nM/4 nM, respectively; also inhibits Ron and Tie2. Phase 1/2.

Storage Conditions

2 years -80 in solvent

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