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OSI-930

Product Specifications

CAS Number

728033-96-3

Target

C-Kit

Applications

Protein Tyrosine Kinase

Smiles

C1=CC=C2C (=C1) C (=CC=N2) CNC3=C (SC=C3) C (=O) NC4=CC=C (C=C4) OC (F) (F) F

Molecular Formula

C22H16F3N3O2S

Additionnal Information

OSI-930 is a potent inhibitor of Kit (c-Kit), KDR and CSF-1R with IC50 of 80 nM, 9 nM and 15 nM, respectively; also potent to Flt-1, c-Raf and Lck and low activity against PDGFRα/β, Flt-3 and Abl. Phase 1.

Storage Conditions

2 years -80 in solvent

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