WZ4002

Product Specifications

CAS Number

1213269-23-8

Target

EGFR

Applications

Protein Tyrosine Kinase

Smiles

CN1CCN (CC1) C2=CC (=C (C=C2) NC3=NC=C (C (=N3) OC4=CC=CC (=C4) NC (=O) C=C) Cl) OC

Molecular Formula

C25H27ClN6O3

Additionnal Information

WZ4002 is a novel, mutant-selective EGFR inhibitor for EGFR (L858R) / (T790M) with IC50 of 2 nM/8 nM in BaF3 cell line; does not inhibit ERBB2 phosphorylation (T798I) .

Storage Conditions

2 years -80 in solvent

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