WZ3146
Product Specifications
CAS Number
1214265-56-1
Target
EGFR
Applications
Protein Tyrosine Kinase
Smiles
CN1CCN (CC1) C2=CC=C (C=C2) NC3=NC=C (C (=N3) OC4=CC=CC (=C4) NC (=O) C=C) Cl
Molecular Formula
C24H25ClN6O2
Additionnal Information
WZ3146 is a mutant-selective irreversible inhibitor of EGFR (L858R) and EGFR (E746_A750) with IC50 of 2 nM and 2 nM; does not inhibit ERBB2 phosphorylation (T798I) .
Storage Conditions
2 years -80 in solvent
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