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MK-8245

Product Specifications

CAS Number

1030612-90-8

Target

SCD

Applications

Metabolism

Smiles

C1CN (CCC1OC2=C (C=CC (=C2) F) Br) C3=NOC (=C3) C4=NN (N=N4) CC (=O) O

Molecular Formula

C17H16BrFN6O4

Additionnal Information

MK-8245 is an liver-targeting inhibitor of stearoyl-CoA desaturase (SCD) with IC50 of 1 nM for human SCD1 and 3 nM for both rat SCD1 and mouse SCD1, with anti-diabetic and anti-dyslipidemic efficacy. Phase 2.

Storage Conditions

2 years -80 in solvent

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