SNS-032 (BMS-387032)
Product Specifications
CAS Number
345627-80-7
Target
CDK
Applications
Cell Cycle
Smiles
CC (C) (C) C1=CN=C (O1) CSC2=CN=C (S2) NC (=O) C3CCNCC3
Molecular Formula
C17H24N4O2S2
Additionnal Information
SNS-032 (BMS-387032) has firstly been described as a selective inhibitor of CDK2 with IC50 of 48 nM in cell-free assays and is 10- and 20-fold selective over CDK1/CDK4. It is also found to be sensitive to CDK7/9 with IC50 of 62 nM/4 nM, with little effect on CDK6. SNS-032 (BMS-387032) induces apoptosis.
Storage Conditions
2 years -80 in solvent
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