AG-490
Product Specifications
CAS Number
133550-30-8
Synonyms
Tyrphostin B42, Zinc02557947
Target
EGFR
Applications
Protein Tyrosine Kinase
Smiles
C1=CC=C (C=C1) CNC (=O) C (=CC2=CC (=C (C=C2) O) O) C#N
Molecular Formula
C17H14N2O3
Additionnal Information
AG-490 is an inhibitor of EGFR with IC50 of 0.1 μM in cell-free assays, 135-fold more selective for EGFR versus ErbB2, also inhibits JAK2 with no activity to Lck, Lyn, Btk, Syk and Src.
Storage Conditions
2 years -80 in solvent
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