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AG-490

Product Specifications

CAS Number

133550-30-8

Synonyms

Tyrphostin B42, Zinc02557947

Target

EGFR

Applications

Protein Tyrosine Kinase

Smiles

C1=CC=C (C=C1) CNC (=O) C (=CC2=CC (=C (C=C2) O) O) C#N

Molecular Formula

C17H14N2O3

Additionnal Information

AG-490 is an inhibitor of EGFR with IC50 of 0.1 μM in cell-free assays, 135-fold more selective for EGFR versus ErbB2, also inhibits JAK2 with no activity to Lck, Lyn, Btk, Syk and Src.

Storage Conditions

2 years -80 in solvent

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