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Vatalanib (PTK787) 2HCl

Product Specifications

CAS Number

212141-51-0

Synonyms

ZK 222584 (cpg-79787) 2HCl

Target

VEGFR

Applications

Protein Tyrosine Kinase

Smiles

C1=CC=C2C (=C1) C (=NN=C2NC3=CC=C (C=C3) Cl) CC4=CC=NC=C4.Cl.Cl

Molecular Formula

C20H15ClN4.2HCl

Additionnal Information

Vatalanib 2HCl (PTK787, ZK 222584, cpg-79787) is an inhibitor of VEGFR2/KDR with IC50 of 37 nM in a cell-free assay, less potent against VEGFR1/Flt-1, 18-fold against VEGFR3/Flt-4. Phase 3.

Storage Conditions

2 years -80 in solvent

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