PF-04217903
Product Specifications
CAS Number
956905-27-4
Target
C-Met
Applications
Protein Tyrosine Kinase
Smiles
C1=CC2=C (C=CC (=C2) CN3C4=NC (=CN=C4N=N3) C5=CN (N=C5) CCO) N=C1
Molecular Formula
C19H16N8O
Additionnal Information
PF-04217903 is a selective ATP-competitive c-Met inhibitor with IC50 of 4.8 nM in A549 cell line, susceptible to oncogenic mutations (no activity to Y1230C mutant) . Phase 1.
Storage Conditions
2 years -80 in solvent
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