Brivanib (BMS-540215)
Product Specifications
CAS Number
649735-46-6
Target
FGFR
Applications
Protein Tyrosine Kinase
Smiles
CC1=CC2=C (N1) C=CC (=C2F) OC3=NC=NN4C3=C (C (=C4) OCC (C) O) C
Molecular Formula
C19H19FN4O3
Additionnal Information
Brivanib is an ATP-competitive inhibitor against VEGFR2 with IC50 of 25 nM, moderate potency against VEGFR-1 and FGFR-1, but >240-fold against PDGFR-β. Phase 3.
Storage Conditions
2 years -80 in solvent
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