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SL-327

Product Specifications

CAS Number

305350-87-2

Target

MEK

Applications

Protein Tyrosine Kinase

Smiles

C1=CC=C (C (=C1) C (=C (N) SC2=CC=C (C=C2) N) C#N) C (F) (F) F

Molecular Formula

C16H12F3N3S

Additionnal Information

SL327 is a selective inhibitor for MEK1/2 with IC50 of 0.18 μM/ 0.22 μM, no activity towards Erk1, MKK3, MKK4, c-JUN, PKC, PKA, or CamKII; capable of transport through the blood-brain barrier.

Storage Conditions

2 years -80 in solvent

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