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PI-103

Product Specifications

CAS Number

371935-74-9

Target

Autophagy

Applications

Autophagy

Smiles

C1COCCN1C2=NC (=NC3=C2OC4=C3C=CC=N4) C5=CC (=CC=C5) O

Molecular Formula

C19H16N4O3

Additionnal Information

PI-103 is a multi-targeted PI3K inhibitor for p110α/β/δ/γ with IC50 of 2 nM/3 nM/3 nM/15 nM in cell-free assays, less potent to mTOR/DNA-PK with IC50 of 30 nM/23 nM. PI-103 induces apoptosis in murine T-cell Lymphoma.

Storage Conditions

2 years -80 in solvent

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