Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Afatinib (BIBW2992)

Product Specifications

CAS Number

850140-72-6

Synonyms

BIBW2992

Target

EGFR

Applications

Protein Tyrosine Kinase

Smiles

CN (C) CC=CC (=O) NC1=C (C=C2C (=C1) C (=NC=N2) NC3=CC (=C (C=C3) F) Cl) OC4CCOC4

Molecular Formula

C24H25ClFN5O3

Additionnal Information

Afatinib inhibits EGFR/ErbB irreversibly in vitro with IC50 of 0.5, 0.4, 10, 14, 1 nM for EGFRwt, EGFR L858R , EGFR L858R/T790M ErbB2 (HER2) and ErbB4 (HER4), respectively. Afatinib induces autophagy.

Storage Conditions

2 years -80 in solvent

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

Biotin Anti-Mouse IFN-γ Antibody[XMG1.2]
E-AB-F1101B-01 25 µg

Biotin Anti-Mouse IFN-γ Antibody[XMG1.2]

Sign In for Pricing
View Details
Biotin Anti-Mouse IFN-γ Antibody[XMG1.2]
E-AB-F1101B-02 100 µg

Biotin Anti-Mouse IFN-γ Antibody[XMG1.2]

Sign In for Pricing
View Details
Aminopyralid
TRC-A628820-50MG 50 mg

Aminopyralid

Sign In for Pricing
View Details
Mesothelin (MSLN) Mouse Monoclonal Antibody (HRP conjugated) [Clone ID: OTI5B12]
TA805171BM 100 µL

Mesothelin (MSLN) Mouse Monoclonal Antibody (HRP conjugated) [Clone ID: OTI5B12]

Sign In for Pricing
View Details
5-Oxo-2-isopropylhexanal
TRC-O856965-2.5G 2.5 g

5-Oxo-2-isopropylhexanal

Sign In for Pricing
View Details
ACOX1 Polyclonal Antibody
E-AB-14479-01 20 µL

ACOX1 Polyclonal Antibody

Sign In for Pricing
View Details