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Nintedanib (BIBF 1120)

Product Specifications

CAS Number

656247-17-5

Synonyms

BIBF 1120, Intedanib

Target

FGFR

Applications

Protein Tyrosine Kinase

Smiles

CN1CCN (CC1) CC (=O) N (C) C2=CC=C (C=C2) N=C (C3=CC=CC=C3) C4=C (NC5=C4C=CC (=C5) C (=O) OC) O

Molecular Formula

C31H33N5O4

Additionnal Information

Nintedanib is a potent triple angiokinase inhibitor for VEGFR1/2/3, FGFR1/2/3 and PDGFRα/β with IC50 of 34 nM/13 nM/13 nM, 69 nM/37 nM/108 nM and 59 nM/65 nM in cell-free assays. Phase 3.

Storage Conditions

2 years -80 in solvent

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